Automatic extraction of cell nuclei from H&E-stained histopathological images

@article{Yi2017AutomaticEO,
  title={Automatic extraction of cell nuclei from H\&E-stained histopathological images},
  author={Faliu Yi and Junzhou Huang and Lin Yang and Yang Xie and Guanghua Xiao},
  journal={Journal of Medical Imaging},
  year={2017},
  volume={4}
}
Abstract. Extraction of cell nuclei from hematoxylin and eosin (H&E)-stained histopathological images is an essential preprocessing step in computerized image analysis for disease detection, diagnosis, and prognosis. We present an automated cell nuclei segmentation approach that works with H&E-stained images. A color deconvolution algorithm was first applied to the image to get the hematoxylin channel. Using a morphological operation and thresholding technique on the hematoxylin channel image… 

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