Automated tetraploid genotype calling by hierarchical clustering

@article{Carley2016AutomatedTG,
  title={Automated tetraploid genotype calling by hierarchical clustering},
  author={Cari A Schmitz Carley and Joseph J. Coombs and David S Douches and Paul C Bethke and Jiwan P. Palta and Richard G. Novy and Jeffrey B. Endelman},
  journal={Theoretical and Applied Genetics},
  year={2016},
  volume={130},
  pages={717-726}
}
New software to make tetraploid genotype calls from SNP array data was developed, which uses hierarchical clustering and multiple F1 populations to calibrate the relationship between signal intensity and allele dosage. SNP arrays are transforming breeding and genetics research for autotetraploids. To fully utilize these arrays, the relationship between signal intensity and allele dosage must be calibrated for each marker. We developed an improved computational method to automate this process… CONTINUE READING