Automated segmentation of the lamina cribrosa using Frangi's filter: a novel approach for rapid identification of tissue volume fraction and beam orientation in a trabeculated structure in the eye

@article{Campbell2015AutomatedSO,
  title={Automated segmentation of the lamina cribrosa using Frangi's filter: a novel approach for rapid identification of tissue volume fraction and beam orientation in a trabeculated structure in the eye},
  author={Ian C. Campbell and Baptiste Coudrillier and Johanne Mensah and Richard L. Abel and C. Ross Ethier},
  journal={Journal of The Royal Society Interface},
  year={2015},
  volume={12}
}
The lamina cribrosa (LC) is a tissue in the posterior eye with a complex trabecular microstructure. This tissue is of great research interest, as it is likely the initial site of retinal ganglion cell axonal damage in glaucoma. Unfortunately, the LC is difficult to access experimentally, and thus imaging techniques in tandem with image processing have emerged as powerful tools to study the microstructure and biomechanics of this tissue. Here, we present a staining approach to enhance the… 

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Scleral structure and biomechanics
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