Automated gating of flow cytometry data via robust model-based clustering.

  title={Automated gating of flow cytometry data via robust model-based clustering.},
  author={Kenneth Lo and Ryan Remy Brinkman and Raphael Gottardo},
  journal={Cytometry. Part A : the journal of the International Society for Analytical Cytology},
  volume={73 4},
The capability of flow cytometry to offer rapid quantification of multidimensional characteristics for millions of cells has made this technology indispensable for health research, medical diagnosis, and treatment. However, the lack of statistical and bioinformatics tools to parallel recent high-throughput technological advancements has hindered this technology from reaching its full potential. We propose a flexible statistical model-based clustering approach for identifying cell populations in… CONTINUE READING

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Fuzzy clustering using scatter matrices

  • PJ Rousseeuw, L Kaufman, E. Trauwaert
  • Comput. Statist. Data Anal
  • 1996
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