Automated detection of local normalization areas for ictal-interictal subtraction brain SPECT.

Abstract

UNLABELLED Whole-brain activity is often chosen to quantitatively normalize peri-ictal and interictal SPECT scans before their subtraction. This use is not justified, because significant and extended modification of the cerebral blood flow can occur during a seizure. We validated and compared 2 automatic methods able to determine the optimal reference… (More)

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