Automated co-culture system for spatiotemporal analysis of cell-to-cell communication.

Abstract

We present a microfluidic co-culture system that generates localized and precisely formulated immune signals among a population of cells, enabling spatiotemporal analysis of paracrine signal transmission between different cell types. The automated system allows us to create temporally modulated chemical inputs that can be delivered to single signal… (More)
DOI: 10.1039/c5lc00182j

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