Automated antinuclear immunofluorescence antibody screening: a comparative study of six computer-aided diagnostic systems.

@article{Bizzaro2014AutomatedAI,
  title={Automated antinuclear immunofluorescence antibody screening: a comparative study of six computer-aided diagnostic systems.},
  author={Nicola Bizzaro and Antonio Graziano Antico and Stefan Platzgummer and Elio Tonutti and Danila Bassetti and Fiorenza Pesente and Renato Tozzoli and Marilina Tampoia and Danilo Villalta},
  journal={Autoimmunity reviews},
  year={2014},
  volume={13 3},
  pages={
          292-8
        }
}
BACKGROUND Indirect immunofluorescence (IIF) plays an important role in immunological assays for detecting and measuring autoantibodies. However, the method is burdened by some unfavorable features: the need for expert morphologists, the subjectivity of interpretation, and a low degree of standardization and automation. Following the recent statement by the American College of Rheumatology that the IIF technique should be considered as the standard screening method for the detection of anti… CONTINUE READING
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