Automated analysis of vapor diffusion crystallization drops with an X-ray beam.

@article{Jacquamet2004AutomatedAO,
  title={Automated analysis of vapor diffusion crystallization drops with an X-ray beam.},
  author={Lilian Jacquamet and J{\'e}r{\'e}my Ohana and Jacques Joly and Franck Borel and Michel Pirocchi and Philippe Charrault and Alain G. Bertoni and Pascale Israel-Gouy and Philippe Carpentier and Frank Kozielski and Delphine Blot and Jean-Luc Ferrer},
  journal={Structure},
  year={2004},
  volume={12 7},
  pages={1219-25}
}
Crystallogenesis, usually based on the vapor diffusion method, is currently considered one of the most difficult steps in macromolecular X-ray crystallography. Due to the increasing number of crystallization assays performed by protein crystallographers, several automated analysis methods are under development. Most of these methods are based on microscope images and shape recognition. We propose an alternative method of identifying protein crystals: by directly exposing the crystallization… CONTINUE READING