Automated analysis of FDG PET as a tool for single-subject probabilistic prediction and detection of Alzheimer’s disease dementia

@article{Arbizu2013AutomatedAO,
  title={Automated analysis of FDG PET as a tool for single-subject probabilistic prediction and detection of Alzheimer’s disease dementia},
  author={Javier Arbizu and Elena Prieto and Pablo Martinez-Lage and Josep Mar{\'i}a Mart{\'i}-Climent and Marta Garc{\'i}a-Granero and Isabel Lamet and Paul A. Pastor and M. Riverol and Maria Teresa Gomez-Isla and I. Pe{\~n}uelas and Jos{\'e} {\'A}ngel Richter and Michael W Weiner},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2013},
  volume={40},
  pages={1394-1405}
}
To introduce, evaluate and validate a voxel-based analysis method of 18F-FDG PET imaging for determining the probability of Alzheimer’s disease (AD) in a particular individual. The subject groups for model derivation comprised 80 healthy subjects (HS), 36 patients with mild cognitive impairment (MCI) who converted to AD dementia within 18 months, 85 non-converter MCI patients who did not convert within 24 months, and 67 AD dementia patients with baseline FDG PET scan were recruited from the AD… CONTINUE READING

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