Automated Screening for Genomic Imbalances using Matrix-Based Comparative Genomic Hybridization

Abstract

Genome-wide screening for chromosomal imbalances using comparative genomic hybridization (CGH) revealed a wealth of data on previously unrecognized tumor-specific genomic alterations. CGH to microarrays of DNA, an approach termed matrix-CGH, allows detection of genomic imbalances at a much higher resolution. We show that matrix CGH is also feasible from… (More)
DOI: 10.1038/labinvest.3780394

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@article{Wessendorf2002AutomatedSF, title={Automated Screening for Genomic Imbalances using Matrix-Based Comparative Genomic Hybridization}, author={Swen Wessendorf and Bj{\"{o}rn Fritz and Gunnar Wrobel and Michelle Nessling and Stefan Lampel and Daniel G{\"{o}ettel and Manfred K{\"{u}epper and Stefan Joos and T. E. Hopman and Felix Kokocinski and Hartmut Doehner and Martin Bentz and Carsten Schw{\"a}enen and Peter Lichter}, journal={Laboratory Investigation}, year={2002}, volume={82}, pages={47-60} }