Automated Grouping of Action Potentials of Human Embryonic Stem Cell-Derived Cardiomyocytes

@article{Gorospe2014AutomatedGO,
  title={Automated Grouping of Action Potentials of Human Embryonic Stem Cell-Derived Cardiomyocytes},
  author={Giann Gorospe and Renjun Zhu and Michal A. Millrod and Elias T. Zambidis and Leslie Tung and Ren{\'e} Vidal},
  journal={IEEE Transactions on Biomedical Engineering},
  year={2014},
  volume={61},
  pages={2389-2395}
}
Methods for obtaining cardiomyocytes from human embryonic stem cells (hESCs) are improving at a significant rate. However, the characterization of these cardiomyocytes (CMs) is evolving at a relatively slower rate. In particular, there is still uncertainty in classifying the phenotype (ventricular-like, atrial-like, nodal-like, etc.) of an hESC-derived cardiomyocyte (hESC-CM). While previous studies identified the phenotype of a CM based on electrophysiological features of its action potential… CONTINUE READING
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