Automated Estimation of Brain Volume in Multiple Sclerosis with BICCR

  title={Automated Estimation of Brain Volume in Multiple Sclerosis with BICCR},
  author={D. Louis Collins and Johan Montagnat and Alex P. Zijdenbos and Alan C. Evans and Douglas L. Arnold},
Neurodegenerative diseases are often associated with loss of brain tissue volume. Our objective was to develop and evaluate a fully automated method to estimate cerebral volume from magnetic resonance images (MRI) of patients with multiple sclerosis (MS). In this study, MRI data from 17 normal subjects and 68 untreated MS patients was used to test the method. Each MRI volume was corrected for image intensity non-uniformity, intensity normalized, brain masked and tissue classified. The… CONTINUE READING
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