Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3

@article{MartnGallardo1992AutomatedDS,
  title={Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3},
  author={Antonia Mart{\'i}n-Gallardo and W. Richard McCombie and J. D. Gocayne and Michael G. FitzGerald and Simon Wallace and B. M. B. Lee and Jane E. Lamerdin and S. Trapp and Jenny M. Kelley and Li Liu and Mark Dubnick and Leslie Johnston-Dow and Anthony R. Kerlavage and Pieter J. de Jong and Anthony Carrano and Chris A. Fields and J. Craig Venter},
  journal={Nature Genetics},
  year={1992},
  volume={1},
  pages={34-39}
}
A total of 116, 118 basepairs (bp) derived from three cosmids spanning the ERCC1 locus of human chromosome 19q13.3 have been sequenced with automated fluorescence-based sequencers and analysed by polymerase chain reaction amplification and computer methods. The assembled sequence forms two contigs totalling 105,831 bp, which contain a human fosB proto-oncogene, a gene encoding a protein phosphatase, two genes of unknown function and the previously-characterized ERCC1 DNA repair gene. This light… 
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Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.
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The sequence and genomic organization of the human Golfα (GNAL) gene were determined and knowledge of the sequence and structure provides essential information for further analysis of the GNAL locus at chromosome 18p11 which has been linked to bipolar disorder and schizophrenia.
cDNA cloning, genomic organization, and expression of the human RTN2 gene, a member of a gene family encoding reticulons.
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Results show differential expression in human tissues with a strikingly high expression of the 1.3-kb transcript in skeletal muscle, which is thought to be responsible for the association of the RTN1 and RTN2 proteins with the endoplasmic reticulum.
ERCC1: A comparative genomic perspective
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The ability to assess novel transcripts and identify candidate regulatory regions demonstrates the potential utility for a catalogue archiving comparative analyses for all genes involved in DNA repair.
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