Automated, high-throughput serum glycoprofiling platform.

  title={Automated, high-throughput serum glycoprofiling platform.},
  author={Henning St{\"o}ckmann and R{\'o}is{\'i}n O'Flaherty and Barbara Adamczyk and Radka Saldova and Pauline M. Rudd},
  journal={Integrative biology : quantitative biosciences from nano to macro},
  volume={7 9},
Complex carbohydrates are rapidly becoming excellent biomarker candidates because of their high sensitivity to pathological changes. However, the discovery of clinical glycobiomarkers has been slow, due to the scarcity of high-throughput glycoanalytical workflows that allow rapid glycoprofiling of large clinical sample sets. To generate high-quality quantitative glycomics data in a high-throughput fashion, we have developed a robotized platform for rapid serum-based N-glycan sample preparation… CONTINUE READING
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