Autologous stem cell transplantation in acute lymphocytic leukemia.

  title={Autologous stem cell transplantation in acute lymphocytic leukemia.},
  author={Norbert Claude Gorin},
  journal={Stem cells},
  volume={20 1},
Autologous stem cell transplantation (ASCT) as well as allogeneic stem cell transplantation and conventional chemotherapy (CT) are less effective at treating acute lymphocytic leukemia (ALL) than acute myelocytic leukemia (AML). Chemoresistance and late relapses are hallmarks of ALL. In this context, the question of whether ASCT is superior to CT remains unanswered. In vitro marrow purging using monoclonal antibodies is not routinely used. This review summarizes the results of ASCT for adult… CONTINUE READING


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Autologous stem cell transplantation in hematological malignancies

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