Autologous smooth muscle cell transplantation improved heart function in dilated cardiomyopathy.

@article{Yoo2000AutologousSM,
  title={Autologous smooth muscle cell transplantation improved heart function in dilated cardiomyopathy.},
  author={Kyung Jong Yoo and R. K.-Y. Li and Richard D. Weisel and Donald A. G. Mickle and Gang Li and Terrence M. Yau},
  journal={The Annals of thoracic surgery},
  year={2000},
  volume={70 3},
  pages={859-65}
}
BACKGROUND Transplantation of myocytes into scarred myocardium has been shown to inhibit ventricular remodeling and maintain myocardial contractility. However, the effect of cell transplantation on hearts with global rather than regional dysfunction is unknown. Therefore, we evaluated the effect of transplantation of autologous smooth muscle cells on the morphometry and function of dilated cardiomyopathic hearts. METHODS Smooth muscle cells were isolated from the ductus deferens of 13-week… CONTINUE READING
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