Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

@inproceedings{Connick2012AutologousMS,
  title={Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study},
  author={Peter Connick and Madhan Kolappan and Charles R. Crawley and Daniel J. Webber and Rickie Patani and Andrew W. Michell and Ming-Qing Du and Shi Lin Luan and Daniel R. Altmann and Alan J. Thompson and Alastair D Compston and Michael Ronal Abingdon Scott and David H. Miller and Siddharthan Chandran},
  booktitle={The Lancet Neurology},
  year={2012}
}
BACKGROUND More than half of patients with multiple sclerosis have progressive disease characterised by accumulating disability. The absence of treatments for progressive multiple sclerosis represents a major unmet clinical need. On the basis of evidence that mesenchymal stem cells have a beneficial effect in acute and chronic animal models of multiple sclerosis, we aimed to assess the safety and efficacy of these cells as a potential neuroprotective treatment for secondary progressive multiple… CONTINUE READING
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