Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy.

@article{Lee2008AutologousMS,
  title={Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy.},
  author={Phil Hye Lee and Jin Wan Kim and Oh Young Bang and Young Hyun Ahn and In Soo Joo and Kenneth Huh},
  journal={Clinical pharmacology and therapeutics},
  year={2008},
  volume={83 5},
  pages={723-30}
}
We evaluated the feasibility and safety of therapy with mesenchymal stem cells (MSCs) through consecutively intra-arterial and three repeated intravenous injections and compared the long-term prognosis between MSC-treated (n=11) and control multiple system atrophy (MSA) patients (n=18). The MSC-treated patients showed significantly greater improvement on the unified MSA rating scale (UMSARS) than the control patients at all visits throughout the 12-month study period. Orthostasis in UMSARS I… CONTINUE READING

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