Autologous immune complex nephritis induced with renal tubular antigen. I. Identification and isolation of the pathogenetic antigen.

@article{Edgington1968AutologousIC,
  title={Autologous immune complex nephritis induced with renal tubular antigen. I. Identification and isolation of the pathogenetic antigen.},
  author={Thomas Scott Edgington and Richard J. Glassock and F. J. Dixon},
  journal={The Journal of experimental medicine},
  year={1968},
  volume={127 3},
  pages={
          555-72
        }
}
The nephritogenic antigen, responsible for the immunogenic stimulus in experimental allergic glomerulonephritis induced with tubular antigen, has been identified as a renal tubular epithelial (RTE)-specific antigen and has been isolated in a relatively purified form. This antigen, RTE-alpha(5), is a distinct and antigenically specific lipoprotein of high density which is derived primarily from the brush border of proximal convoluted tubular epthelium of the rat kidney. It has been suggested… CONTINUE READING
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