Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS.

@article{Mancardi2001AutologousHS,
  title={Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS.},
  author={Giovanni Luigi Mancardi and Riccardo Saccardi and Massimo Filippi and Francesca Gualandi and Alessandra Murialdo and M. Inglese and Maria Giovanna Marrosu and Giuseppe Meucci and Luca Massacesi and Alessandra Lugaresi and Francesca Pagliai and Maria Pia Sormani and Francesco Sardanelli and Alberto Marmont},
  journal={Neurology},
  year={2001},
  volume={57 1},
  pages={62-8}
}
BACKGROUND Autologous hematopoietic stem cell transplantation (ASCT) has been recently utilized with encouraging results in patients with poorly controlled MS. OBJECTIVE To determine in severe cases of MS the effect of ASCT on gadolinium (Gd)-enhanced MRI and to obtain information on clinical course and safety. METHODS In a cooperative study, 10 patients with rapidly evolving secondary progressive MS were transplanted, after BEAM conditioning regimen (carmustine, etoposide, cytosine… CONTINUE READING
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