Autologous hematopoietic stem cell transplantation modulates immunocompetent cells and improves β-cell function in Chinese patients with new onset of type 1 diabetes.

@article{Li2012AutologousHS,
  title={Autologous hematopoietic stem cell transplantation modulates immunocompetent cells and improves β-cell function in Chinese patients with new onset of type 1 diabetes.},
  author={Lirong Li and Shanmei Shen and Jian Ouyang and Yun Long Hu and Limin Hu and Weijuan Cui and Ning Zhang and Yu-zheng Zhuge and Bing Chen and Jingyan Xu and Dalong Zhu},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 5},
  pages={1729-36}
}
CONTEXT Autologous hematopoietic stem cell transplantation (AHSCT) has the potential to induce clinical remission in patients with newly diagnosed type 1 diabetes. OBJECTIVE The objective of the study was to examine the impact of AHSCT on lymphocytes and pancreatic β-cell function. DESIGN This was a nonrandomized, open-label prospective study. PATIENTS AND INTERVENTIONS Thirteen patients with new onset of type 1 diabetes, 10 of them with diabetic ketoacidosis, were subjected to AHSCT with… CONTINUE READING

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