Autologous haematopoietic stem cell transplantation without CD34+ cell selection in refractory Crohn's disease.

@article{Cassinotti2008AutologousHS,
  title={Autologous haematopoietic stem cell transplantation without CD34+ cell selection in refractory Crohn's disease.},
  author={Andrea Cassinotti and Claudio Annaloro and Sandro Ardizzone and Francesco Onida and Aldo Della Volpe and Mario Clerici and Patrizia Usardi and Salvatore Greco and Giovanni Maconi and Gabriele Bianchi Porro and Giorgio Lambertenghi Deliliers},
  journal={Gut},
  year={2008},
  volume={57 2},
  pages={211-7}
}
OBJECTIVES Autologous haematopoietic stem cell transplantation (HSCT) with CD34(+) cell selection has recently been used in the treatment of refractory Crohn's disease, showing good safety and promising efficacy. We investigated the safety and efficacy of HSCT with unselected peripheral blood stem cells (PBSCs) in moderate-severe refractory Crohn's disease. PATIENTS Four patients (three male, one female; age range 26-45 years) with active moderate-severe Crohn's disease (median Crohn's… CONTINUE READING
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