Autologous dendritic cell vaccines for non-small-cell lung cancer.

  title={Autologous dendritic cell vaccines for non-small-cell lung cancer.},
  author={Edward A. Hirschowitz and Terry Foody and Richard Kryscio and Larry G Dickson and Jamie L Sturgill and John R. Yannelli},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={22 14},
PURPOSE Therapeutic outcomes of definitively treated non-small-cell lung cancer (NSCLC) are unacceptably poor. A wealth of preclinical information, and a modest amount of clinical information indicate that dendritic cell (DC) vaccines have therapeutic potential. Only a handful of NSCLC patients have been included in DC clinical trials. We delivered autologous DC vaccines to 16 individuals with stage IA to IIIB NSCLC treated with surgery, chemoradiation, or multimodality therapy. The objectives… CONTINUE READING
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