Autologous bone marrow transplantation for acute leukaemia in remission.

@article{Gorin1986AutologousBM,
  title={Autologous bone marrow transplantation for acute leukaemia in remission.},
  author={N. C. Gorin and Patrick Herv{\'e} and Philippe Aegerter and Anthony H. Goldstone and David Christopher Linch and Dominique Maraninchi and A J Burnett and Werner Helbig and Giovanna Meloni and Leo F. Verdonck},
  journal={British journal of haematology},
  year={1986},
  volume={64 2},
  pages={385-95}
}
Between 1980 and 1985, 175 patients with acute leukaemia in first or subsequent complete remission (CR) were treated by chemotherapy or chemoradiotherapy followed by transfusion of autologous bone marrow cells that had been collected days or months previously. In 85 cases, autologous marrow cells were treated ex vivo with cytotoxic drugs or monoclonal antibodies with the intention of removing residual leukaemic cells. The actuarial relapse-free rate was 52% at 2 years. Of 89 patients… CONTINUE READING