Autologous bone marrow transplantation for acute lymphoblastic leukemia.

  title={Autologous bone marrow transplantation for acute lymphoblastic leukemia.},
  author={Stephen E. Sallan and Charlotte Marie Niemeyer and Amy L Billett and Jeffrey M Lipton and Nancy J. Tarbell and Richard D. Gelber and Christine Murray and Timothy P Pittinger and Lawrence C Wolfe and Robert C. Bast},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={7 11},
Forty-four children with acute lymphoblastic leukemia (ALL) who had relapsed (N = 43) or had refractory disease (N = 1) were intensively treated with combination chemotherapy, had remission bone marrow (BM) harvested and purged in vitro with monoclonal antibodies specific for leukemia-associated antigens, underwent postharvest ablative chemotherapy and radiotherapy and subsequently were infused with their autologous marrow. Of the 44 patients treated between November 1980 and January 1988, 19… CONTINUE READING


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