Autologous bone-marrow stem-cell transplantation for myocardial regeneration

@article{Stamm2003AutologousBS,
  title={Autologous bone-marrow stem-cell transplantation for myocardial regeneration},
  author={C. Stamm and B. Westphal and Hans-Dieter Kleine and M. Petzsch and Prof. Dr. med. Gustav Steinhoff},
  journal={The Lancet},
  year={2003},
  volume={361},
  pages={45-46}
}
  • C. Stamm, B. Westphal, +2 authors Prof. Dr. med. Gustav Steinhoff
  • Published 2003
  • Medicine
  • The Lancet
  • Implantation of bone-marrow stem cells in the heart might be a new method to restore tissue viability after myocardial infarction. We injected up to 1.5x10(6) autologous AC133+ bone-marrow cells into the infarct border zone in six patients who had had a myocardial infarction and undergone coronary artery bypass grafting. 3-9 months after surgery, all patients were alive and well, global left-ventricular function was enhanced in four patients, and infarct tissue perfusion had improved strikingly… CONTINUE READING

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    The primary objective is to analyze the safety and efficacy of CD133+ cells, obtained from peripheral blood in the treatment of diabetic patients with critic ischemia in lower limbs… Expand
    ConditionsDiabetic Patients With Critic Ischemia in Lower Limbs Who Are Administered With CD133+ Cells Mobilized by G-CSF
    InterventionBiological
    INTERVENTIONAL CLINICAL TRIAL
    Cell transplantation for treatment of heart failure is a novel field of translational research that offers the perspective of developing curative approaches by regenerating or… Expand
    ConditionsCongestive Heart Failure, Coronary Artery Disease With Need for Bypass Surgery, Myocardial Ischemia, Angina Pectoris, (+1 more)
    InterventionProcedure
    INTERVENTIONAL CLINICAL TRIAL
    The aim of this study is to evaluate if the intracoronary infusion of autologous bone-marrow derived CD133+ endothelial precursor cells is able to promote neovascularization and to… Expand
    ConditionsCoronary Artery Disease
    InterventionProcedure
    Transplant of autologous bone marrow stem cells in ischemic heart disease

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