• DOI:10.1016/S0140-6736(03)12110-1
Corpus ID: 23858666

Autologous bone-marrow stem-cell transplantation for myocardial regeneration

@article{Stamm2003AutologousBS,
  title={Autologous bone-marrow stem-cell transplantation for myocardial regeneration},
  author={C. Stamm and B. Westphal and H. Kleine and M. Petzsch and Prof. Dr. med. Gustav Steinhoff},
  journal={The Lancet},
  year={2003},
  volume={361},
  pages={45-46}
}

• C. Stamm, B. Westphal, +2 authors Prof. Dr. med. Gustav Steinhoff
• Published 2003
• Medicine
• The Lancet

Implantation of bone-marrow stem cells in the heart might be a new method to restore tissue viability after myocardial infarction. We injected up to 1.5x10(6) autologous AC133+ bone-marrow cells into the infarct border zone in six patients who had had a myocardial infarction and undergone coronary artery bypass grafting. 3-9 months after surgery, all patients were alive and well, global left-ventricular function was enhanced in four patients, and infarct tissue perfusion had improved strikingly… Expand