Autologous and allogeneic mesenchymal stem cells in organ transplantation: what do we know about their safety and efficacy?

@article{Alagesan2014AutologousAA,
  title={Autologous and allogeneic mesenchymal stem cells in organ transplantation: what do we know about their safety and efficacy?},
  author={Senthilkumar Alagesan and Matthew D Griffin},
  journal={Current opinion in organ transplantation},
  year={2014},
  volume={19 1},
  pages={65-72}
}
PURPOSE OF REVIEW Recent developments toward the successful clinical application of autologous and allogeneic mesenchymal stem cells (MSCs) to organ transplantation are summarized with a focus on safety and efficacy. RECENT FINDINGS Clinical trials in organ transplantation and other conditions indicate that infusion of autologous or allogeneic MSCs is generally well tolerated. However, new studies also suggest that efficacy may be curtailed by sequestration in the lungs and early elimination… CONTINUE READING
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