Autoinhibition of TFIIIB70 binding by the tetratricopeptide repeat-containing subunit of TFIIIC.

Abstract

An important step in the assembly of RNA polymerase (pol) III transcription complexes on tRNA and 5 S genes is the interaction between the tetratricopeptide repeat (TPR)-containing subunit of TFIIIC (TFIIIC131) and the TFIIB-related subunit of TFIIIB (TFIIIB70/Brf1). A fragment of TFIIIC131 that contains the hydrophilic amino terminus and two TPR arrays… (More)

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@article{Moir2002AutoinhibitionOT, title={Autoinhibition of TFIIIB70 binding by the tetratricopeptide repeat-containing subunit of TFIIIC.}, author={Robyn D. Moir and Karen V. Puglia and Ian M. Willis}, journal={The Journal of biological chemistry}, year={2002}, volume={277 1}, pages={694-701} }