Autoinflammatory bone disorders.

  title={Autoinflammatory bone disorders.},
  author={Henner Morbach and Christian M Hedrich and Meinrad Joachim Beer and Hermann Joseph Girschick},
  journal={Clinical immunology},
  volume={147 3},
Autoinflammatory bone disorders are characterized by chronic non-infectious osteomyelitis and inflammation-induced bone resorption and result from aberrant activation of the innate immune system. Sporadic chronic non-bacterial osteomyelitis (CNO) is the most common disease subtype. The clinical picture is highly variable and the exact underlying pathophysiology remains to be determined. Recently, novel insights in the pathophysiology of sterile bone inflammation have been gathered by analyzing… CONTINUE READING


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