Autoimmunity vs. cancer: predator vs. alien?

  title={Autoimmunity vs. cancer: predator vs. alien?},
  author={Christian Berens and Kirsten Lauber and Martin Herrmann},
  volume={46 5},
"The enemy of my enemy is my friend." According to this motto, the human protagonists in Paul W. S. Anderson's science-fiction movie "Alien vs. Predator" (2004) solidarize with a predator in order to fight the aliens. Can this ancient and simple logic be transferred to the field of oncology and cancer immunotherapy? Can we utilize mechanisms known from the context of autoimmunity to fight cancer? Here, we summarize immune cell-mediated detection of danger and damage, central and peripheral… CONTINUE READING