Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease: a prospective cohort study.

@article{Vermeire2003AutoimmunityAW,
  title={Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease: a prospective cohort study.},
  author={S{\'e}verine Vermeire and M. Nasimul Noman and Gert A Van Assche and Filip Baert and Kristel van Steen and Nele Esters and Sofie Joossens and Xavier Bossuyt and P. R. Rutgeerts},
  journal={Gastroenterology},
  year={2003},
  volume={125 1},
  pages={32-9}
}
BACKGROUND & AIMS Infliximab therapy is an effective approach to treating Crohn's disease. Development of antinuclear antibodies has been described in patients treated, but the size of the problem and the relationship with autoimmunity have not been investigated. We investigated the occurrence of antinuclear antibodies in 125 consecutive Crohn's disease… CONTINUE READING