Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection.

@article{Betterle2000AutoimmunityAP,
  title={Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection.},
  author={Corrado Betterle and Paolo Fabris and Renato Zanchetta and Beniamino Pedini and Giulia Tositti and Emanuele Bosi and Fausto de Lalla},
  journal={Diabetes care},
  year={2000},
  volume={23 8},
  pages={1177-81}
}
OBJECTIVE The aim of the study was to investigate the prevalence of clinical and latent autoimmune diseases in Italian patients with hepatitis C virus (HCV) chronic infection before and after treatment with interferon-alpha (IFN-alpha). RESEARCH DESIGN AND METHODS The evidence of clinical autoimmune disease and the presence of autoantibodies were assessed in 70 patients with HCV chronic infection. Autoantibodies to islet cell (ICA), glucagon-producing cells (GCA), parietal cell (PCA), adrenal… CONTINUE READING