Autoimmune thyroiditis with severe hypothyroidism resistant to the treatment with high peroral doses of thyroxine: case report.

@article{Payer2000AutoimmuneTW,
  title={Autoimmune thyroiditis with severe hypothyroidism resistant to the treatment with high peroral doses of thyroxine: case report.},
  author={Juraj Payer and K Sl{\'a}dekov{\'a} and Soňa Kiňov{\'a} and Z Cesnakov{\'a} and Zdenko Killinger and Mari{\'a}n Krizko and Iwar Klime{\vs} and Pavel Langer},
  journal={Endocrine regulations},
  year={2000},
  volume={34 4},
  pages={189-93}
}
Female patient (42 yr) suffered from autoimmune thyroiditis resulting in severe hypothyroidism. She was treated for several years by district physician with the dose of 150 microg L-thyroxine daily. Since the level of TSH was repeatedly very high and no improvement of clinical signs has been observed, she was referred to the Medical Faculty Hospital. Thyroid ultrasound showed remarkable diffuse hypoechogenicity, thyroid scintigraphy showed enlarged thyroid with low 99mTc uptake, TRH test was… CONTINUE READING