Autoimmune pulmonary alveolar proteinosis: treatment options in year 2013.

  title={Autoimmune pulmonary alveolar proteinosis: treatment options in year 2013.},
  author={Steffen T. Leth and Elisabeth Bendstrup and Hanne Thang Vestergaard and Ole Hilberg},
  volume={18 1},
Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of a periodic acid Schiff (PAS)-positive eosinophilic material in the distal airways. For decades, the standard treatment of PAP has been whole lung lavage (WLL), where large quantities of saline are instilled into the lungs to remove the proteinaceous material. However, not all patients respond to this treatment. Thus, new treatment modalities, such as subcutaneous or inhaled granulocyte macrophage colony… CONTINUE READING
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