Autoimmune odyssey on the Aegean Sea

  title={Autoimmune odyssey on the Aegean Sea},
  author={Mark J. Mamula and Donna L Farber and George C Tsokos},
  journal={Nature Immunology},
The origins of autoimmune disease typically require intracellular interactions not unlike those found in immunity elicited to foreign antigens: a source of self antigen and its presentation, leading to the activation of both B and T lymphocytes1,2. It is now recognized that elements of the innate immune response are also critical for the induction of… CONTINUE READING