Autoimmune modulation of astrocyte-mediated homeostasis

@article{Korn2007AutoimmuneMO,
  title={Autoimmune modulation of astrocyte-mediated homeostasis},
  author={Thomas Korn and Mahendra Rao and Tim Magnus},
  journal={NeuroMolecular Medicine},
  year={2007},
  volume={9},
  pages={1-15}
}
Astrocytes are principal mediators of homeostasis in the central nervous system (CNS). They supply neurons and oligodendrocytes with substrates for energy metabolism and clear the extracellular space of excess neurotransmitters. In neuroinflammation, astrocytes have classically been regarded as unimportant since their capacity to present antigen to T cells is limited and has been questioned in vivo. However, it is an evolving concept that autoimmunity in the CNS has a profound impact on… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
2 Extracted Citations
107 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 107 references

Betalactam antibiotics offer neuroprotection by increasing glutamate transporter expression

  • J D.Rothstein, S. Patel, M RRegan
  • Nature 433,
  • 2005

Similar Papers

Loading similar papers…