Autoimmune lymphoproliferative syndrome (ALPS). Case report and family history.

@article{Ries2010AutoimmuneLS,
  title={Autoimmune lymphoproliferative syndrome (ALPS). Case report and family history.},
  author={F. Ries and Alina Ferster and Fr{\'e}d{\'e}ric Rieux-Laucat and Arielle Biwer and Mario A. Dicato},
  journal={Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg},
  year={2010},
  volume={2},
  pages={271-8}
}
Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease caused by defective lymphocyte apoptosis and is characterized by non-malignant lymphoproliferation, hepatosplenomegaly, autoimmune manifestations and increased risk of both Hodgkin's and non-Hodgkin's lymphoma. Most forms of the disease are due to germ line mutations of the FAS gene and… CONTINUE READING