Autoimmune liver diseases in children - what is different from adulthood?

  title={Autoimmune liver diseases in children - what is different from adulthood?},
  author={Giorgina Mieli-Vergani and Diego Vergani},
  journal={Best practice & research. Clinical gastroenterology},
  volume={25 6},
Autoimmune liver disorders in childhood include autoimmune hepatitis, autoimmune sclerosing cholangitis and de novo autoimmune hepatitis after liver transplant. These inflammatory liver disorders are characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by autoantibodies and increased levels of immunoglobulin G. Autoimmune hepatitis is particularly aggressive in children and progresses rapidly unless immunosuppressive treatment is… CONTINUE READING