Autoimmune hepatitis in children: an overview of the disease focusing on current therapies.

@article{Corte2012AutoimmuneHI,
  title={Autoimmune hepatitis in children: an overview of the disease focusing on current therapies.},
  author={Claudia Della Corte and Maria Rita Sartorelli and Carmen Donatella Sindoni and Elia Girolami and Luigi Giovannelli and Donatella Comparcola and Valerio Nobili},
  journal={European journal of gastroenterology & hepatology},
  year={2012},
  volume={24 7},
  pages={739-46}
}
Autoimmune hepatitis (AIH) is an immune-mediated necroinflammatory disease of the liver characterized by elevation of IgG, presence of characteristic autoantibodies, and histological features of interface hepatitis. Two types of juvenile AIH have been recognized according to seropositivity for smooth muscle and/or antinuclear antibody (AIH type 1) or liver kidney microsomal antibody (AIH type 2). The exact pathogenesis of AIH is still unclear, but it is known that unidentified environmental… CONTINUE READING
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