Autoimmune gastropathy in type 1 diabetic patients with parietal cell antibodies: histological and clinical findings.

@article{Block2003AutoimmuneGI,
  title={Autoimmune gastropathy in type 1 diabetic patients with parietal cell antibodies: histological and clinical findings.},
  author={Cheryl D. Block and Ivo H De Leeuw and J. Bogers and Paul A. Pelckmans and Margareta M. Ieven and E A Van marck and Kristien L Van Acker and L Van Gaal},
  journal={Diabetes care},
  year={2003},
  volume={26 1},
  pages={82-8}
}
OBJECTIVE Approximately 15-20% of type 1 diabetic patients exhibit parietal cell antibodies (PCAs) targeting gastric H+/K+ATPase. We examined whether iron deficiency anemia, pernicious anemia, and autoimmune gastritis, which may predispose to gastric tumors, were more frequent in PCA+ than in PCA- patients. RESEARCH DESIGN AND METHODS Gastric biopsies from 88 consecutively recruited type 1 diabetic patients (51 men and 37 women, 47 PCA+ and 41 PCA-, aged 42 +/- 13 years) were evaluated using… CONTINUE READING

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LF, the Belgian Diabetes Registry: Gastric parietal cell antibodies are associated with glutamic acid decarboxylase-65 antibodies and the HLA DQA1*0501DQB1*0301 haplotype in type 1 diabetes

  • CEM De Block, IH De Leeuw, RPA Rooman, F Winnock, MVL Du Caju, Gaal Van
  • Diabet Med 17:618–622,
  • 2000
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Decochez Figure 1—Schematic presentation of manifestations of autoimmune gastropathy. Pathogenetic considerations and a possible role of PCA are discussed in the CONCLUSIONS section

  • CEM De Block, IH De Leeuw
  • DIABETES CARE, VOLUME 26,
  • 2003

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