Autoimmune diseases after hepatitis B immunization in adults: Literature review and meta-analysis, with reference to 'autoimmune/autoinflammatory syndrome induced by adjuvants' (ASIA).

@article{Elwood2018AutoimmuneDA,
  title={Autoimmune diseases after hepatitis B immunization in adults: Literature review and meta-analysis, with reference to 'autoimmune/autoinflammatory syndrome induced by adjuvants' (ASIA).},
  author={J Mark Elwood and Rohan Ameratunga},
  journal={Vaccine},
  year={2018},
  volume={36 38},
  pages={
          5796-5802
        }
}
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13 Citations
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13 Citations

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Six key topics that have been at the centre of global discussions on vaccine safety during the early 21st century are summarized: thiomersal in multi-dose non-live vaccines, aluminium adjuvants used with several non- live vaccines, autism and auto-immune conditions as possible consequences of vaccination, a risk of immune overload with increasing numbers of vaccinations, and detrimental non-specific effects (NSEs) of vaccination.
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References

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Autoimmunity following Hepatitis B vaccine as part of the spectrum of ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’ (ASIA): analysis of 93 cases
TLDR
Common clinical characteristics were observed among 93 patients diagnosed with immune-mediated conditions post-HBVv, suggesting a common denominator in these diseases, and the ASIA criteria were found to be very useful among adults with post- vaccination events.
Chronic fatigue syndrome and fibromyalgia following immunization with the hepatitis B vaccine: another angle of the ‘autoimmune (auto-inflammatory) syndrome induced by adjuvants’ (ASIA)
TLDR
It is suggested that in some cases CFS and FM can be temporally related to immunization, as part of ASIA syndrome, as a result of the plausible link between ASIA and CFS/FM.
Revisiting adverse reactions to vaccines: A critical appraisal of Autoimmune Syndrome Induced by Adjuvants (ASIA).
Safety and efficacy of hepatitis B vaccine in systemic lupus erythematosus
TLDR
Hepatitis B vaccination was safe in inactive SLE patients with an adequate vaccine response rate and no significant change in mean SLEDAI score was detected after each dose throughout the study.
A one year followup of chronic arthritis following rubella and hepatitis B vaccination based upon analysis of the Vaccine Adverse Events Reporting System (VAERS) database.
TLDR
Adult rubella and adult hepatitis B vaccines were statistically associated with chronic arthritis which persisted for at least one year, and the etiology for these adverse reactions may involve autoimmune mechanisms.
Central nervous system demyelinating diseases and recombinant hepatitis B vaccination: a critical systematic review of scientific production
TLDR
A critical systematic review aimed at assessing whether hepatitis B vaccination increases the risk of onset or relapse of multiple sclerosis and other central nervous system demyelinating diseases concluded that on the basis of current data there is no need to modify the vaccination recommendations.
The epidemiological profile of ASIA syndrome after HPV vaccination: an evaluation based on the Vaccine Adverse Event Reporting Systems
TLDR
This study presents the first systematic estimation of ASIA incidence and expands the knowledge on this pathology by carrying out an analysis of the VAERS database to retrieve all cases of suspected ASIA syndrome.
Epidemiology of autoimmune reactions induced by vaccination.
TLDR
The evidence for and against vaccination as a risk factor for AID are discussed to highlight what is known and what remains to be explored, and the type of epidemiological evidence that would be required to better address the issues.
Evidence Refuting the Existence of Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA).
Development of multiple sclerosis after vaccination against hepatitis B: a study based on human leucocyte antigen haplotypes.
TLDR
There was no difference in the clinical features between vaccinated and nonvaccinated MS patients, and this study supports recent reports that hepatitis B vaccination is safe in MS patients and that hepatitisB vaccination is not involved in the development of MS.
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