Autoimmune disease. A problem of defective apoptosis.

Abstract

Human autoimmune diseases share the common feature of an imbalance between the production and destruction of various cell types including lymphocytes (SLE), synovial cells (RA), and fibroblasts (scleroderma). Patients with SLE have increased levels of soluble Fas that inhibit proper apoptosis of lymphocytes. In animal models of autoimmune diseases… (More)

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Cite this paper

@article{Mountz1994AutoimmuneDA, title={Autoimmune disease. A problem of defective apoptosis.}, author={James Mountz and Joseph Wu and J. Cheng and T. Zhou}, journal={Arthritis and rheumatism}, year={1994}, volume={37 10}, pages={1415-20} }