Autoimmune aspects in glaucoma.

  title={Autoimmune aspects in glaucoma.},
  author={Nadine von Thun und Hohenstein-Blaul and Katharina Bell and Norbert Pfeiffer and Franz Herman Grus},
  journal={European journal of pharmacology},
The pathogenesis of glaucoma, a common neurodegenerative disease, involves an immunologic component. Studies demonstrate changes of autoantibody concentrations against retinal and optic nerve head antigens in glaucoma patients. Furthermore we found antibody deposits in human glaucomatous retinae in a pro-inflammatory environment. Clinical studies showed up regulated, but also significantly down-regulated autoantibody levels. These antibodies belong to the natural autoimmunity. The upregulation… CONTINUE READING