Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Novel Meningoencephalomyelitis.

  title={Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Novel Meningoencephalomyelitis.},
  author={Boyan Fang and Andrew Mckeon and Shannon R. Hinson and Thomas J. Kryzer and Sean J. Pittock and Allen J. Aksamit and Vanda A. Lennon},
  journal={JAMA neurology},
  volume={73 11},
Importance A novel astrocytic autoantibody has been identified as a biomarker of a relapsing autoimmune meningoencephalomyelitis that is immunotherapy responsive. Seropositivity distinguishes autoimmune glial fibrillary acidic protein (GFAP) meningoencephalomyelitis from disorders commonly considered in the differential diagnosis. Objective To describe a novel IgG autoantibody found in serum or cerebrospinal fluid that is specific for a cytosolic intermediate filament protein of astrocytes… CONTINUE READING
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