Autocrine production of epithelial cell-derived neutrophil attractant-78 induced by granulocyte colony-stimulating factor in neutrophils.

@article{Suzuki2002AutocrinePO,
  title={Autocrine production of epithelial cell-derived neutrophil attractant-78 induced by granulocyte colony-stimulating factor in neutrophils.},
  author={Sachiko Suzuki and Masanobu Kobayashi and Kouji Chiba and Iori Horiuchi and Jingxin Wang and Takeshi Kondoh and Satoshi Hashino and Junji Tanaka and Masuo Hosokawa and Masahiro Asaka},
  journal={Blood},
  year={2002},
  volume={99 5},
  pages={
          1863-5
        }
}
Whereas mobilization to inflammatory sites is an important function of neutrophils, it remains to be determined whether granulocyte colony-stimulating factor (G-CSF) stimulates the mobilization of neutrophils to the inflammatory sites. This study compared the expression of more than 9000 genes in neutrophils treated with and without G-CSF with the use of a DNA microarray system to determine the effects of G-CSF on the function of neutrophils. It was found that messenger RNA expression of… CONTINUE READING

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