Autocrine and paracrine growth regulation of breast cancer: Clinical implications

  title={Autocrine and paracrine growth regulation of breast cancer: Clinical implications},
  author={Charles Osborne and Carlos L. Arteaga},
  journal={Breast Cancer Research and Treatment},
Research using experimental models of human breast cancer has broadened our understanding of the possible biochemical pathways regulating breast cancer growth. Breast cancer cells express receptors for and respond to a variety of steroid and polypeptide hormones and growth factors. Specific oncogenes are also expressed in breast cancer cells, and levels of expression may relate to tumor growth and aggressiveness. Recent studies have shown that breast cancer cells can even synthesize and secrete… CONTINUE READING
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Insulin-like growth factor II (IGFII): A potential autocrine growth factor for human breast cancer (Abstract)

  • E Coronado, K Ramasharma, +4 authors K Osborne
  • Proc Am Assoc Cancer Res
  • 1988
2 Excerpts

MarAutocrine and paracrine growth regulation

  • AR Hanauske, CL Arteaga, GM Clark, J Buchok
  • 1988
1 Excerpt

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