Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin.

@article{Marzioni2005AutocrineparacrineRO,
  title={Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin.},
  author={Marco Marzioni and Shannon S. Glaser and Heather Francis and Luca Marucci and Antonio Benedetti and Domenico Alvaro and Silvia Taffetani and Yoshiyuki Ueno and Tania A Roskams and Jo Lynne Phinizy and Juliet Venter and Giammarco Fava and Gene D Lesage and Gianfranco Alpini},
  journal={Gastroenterology},
  year={2005},
  volume={128 1},
  pages={
          121-37
        }
}
  • Marco Marzioni, Shannon S. Glaser, +11 authors Gianfranco Alpini
  • Published in Gastroenterology 2005
  • Biology, Medicine
  • BACKGROUND & AIMS The biliary tree is the target of cholangiopathies that are chronic cholestatic liver diseases characterized by loss of proliferative response and enhanced apoptosis of cholangiocytes, the epithelial cells lining the biliary tree. The endogenous factors that regulate cholangiocyte proliferation are poorly understood. Therefore, we studied the role of the neuroendocrine hormone serotonin as a modulator of cholangiocyte proliferation. METHODS The presence of the serotonin 1A… CONTINUE READING

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