Autocrine, paracrine and juxtacrine signaling by EGFR ligands.

  title={Autocrine, paracrine and juxtacrine signaling by EGFR ligands.},
  author={Amar Bahadur Singh and Raymond C Harris},
  journal={Cellular signalling},
  volume={17 10},
Receptor and cytoplasmic protein tyrosine kinases play prominent roles in the control of a range of cellular processes during embryonic development and in the regulation of many metabolic and physiological processes in a variety of tissues and organs. The epidermal growth factor receptor (EGFR) is a well-known and versatile signal transducer that has been highly conserved during evolution. It functions in a wide range of cellular processes, including cell fate determination, proliferation, cell… CONTINUE READING


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