Autoantibody to gp50, a glycoprotein shared in common between fibroblasts and lymphocytes, in progressive systemic sclerosis.

Abstract

Five out of 51 sera (10%) from patients with progressive systemic sclerosis reacted by immunoblotting with tissue concanavalin A binding glycoproteins of 50 kD and 45 kD Mr, whereas only one out of 133 control sera gave the same reaction (P less than 0.001). The antigens were localized to the microsomal fractions of tissues and were eluted from concanavalin… (More)

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@article{Alderuccio1989AutoantibodyTG, title={Autoantibody to gp50, a glycoprotein shared in common between fibroblasts and lymphocytes, in progressive systemic sclerosis.}, author={Frank Alderuccio and Deborah A. Witherden and B. H. Toh and Allain J. Barnett}, journal={Clinical and experimental immunology}, year={1989}, volume={78 1}, pages={26-30} }