Autoantibody to NA14 is an independent marker primarily for Sjogren's syndrome.

  title={Autoantibody to NA14 is an independent marker primarily for Sjogren's syndrome.},
  author={Kazuhisa Nozawa and Keigo Ikeda and Minoru Satoh and Westley H. Reeves and Carol M. Stewart and Yueh-Chun Li and Tim J. Yen and Rosa M Rios and Kenji Takamori and Hideoki Ogawa and Iwao Sekigawa and Yoshinari Takasaki and Edward K L Chan},
  journal={Frontiers in bioscience},
Nuclear Autoantigen of 14 kDa (NA14) was originally identified using the serum of a Sjögren's syndrome (SS) patient as probe in screening a human testis cDNA expression library. To date there is no report in the systematic analysis of the prevalence of autoantibodies to NA14. In this study, anti-NA14 was determined in several rheumatic diseases from independent cohorts in the US and Japan. The prevalence of anti-NA14 were 18/132 (13.6%) in primary SS, 0/50 (0%) secondary SS, 2/100 (2%) SLE, 1… CONTINUE READING


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